1982 Supplement to DNA Replication

after antibiotics are halted; however, except for small numbers of cases, this does not seem to be the case. Even microbes, such as Neisseria gonorrhoeae, that produce CWDB naturally appear to be curable with penicillin. Most intriguing, however, is the role of CWDB in diseases in which there is no known etiological agent, but appear to be infectious in nature. Most prominent of these are sarcoidosis, Whipple's disease, and aphthous stomatitis. Naturally, the authors of these chapters, since they are working in the field, make a strong case for CWDB involvement in many infectious diseases. On balance, it should be stated that we do not yet know the conclusive role of CWDB in human infection. Of particular usefulness to individuals wishing to pursue the study of CWDB are the appendices. The editor and his associates describe in detail the materials and methods required to study this type of microbe. In sum, this work is a complete and scholarly review of microbes without cell walls. Occasionally, some points and concepts are too overstated, and this detracts from the inherent solid scientific evidence presented. This book should be a useful reference for those microbiologists interested in working with a type of microbe that may have considerable clinical significance and about which not much is known.